AVEO Oncology Announces Completion of a CHMP Oral Explanation for Tivozanib as a Treatment of First-Line Renal Cell Carcinoma

CAMBRIDGE, Mass. --  AVEO Oncology (NASDAQ:AVEO) today announced its European licensee for tivozanib, EUSA Pharma, has completed an oral explanation to the Committee for Medicinal Products for Human Use (CHMP), the scientific committee of the European Medicines Agency (EMA), as part of the Marketing Authorization Application (MAA) review process for tivozanib as a treatment for patients with first-line renal cell carcinoma (RCC). It is expected that with the oral explanation complete, the CHMP will proceed to an opinion which they will submit to the European Commission (EC), which has the authority to approve medicines for use in the 28 countries in the European Union. The opinion is expected to be announced at a future CHMP meeting.
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GlycoMimetics Announces High Overall Response Rates, Low Induction Mortality,  Promising Initial Survival Outcomes, and Supportive Biomarker Data from Phase 1/2 Trial of GMI-1271 in AML

Company to provide update and host conference call today on clinical data to be presented at 2017 ASCO and EHA Meetings
 
ROCKVILLE, Md. --  GlycoMimetics, Inc. (NASDAQ: GLYC) today announced the release of abstracts containing new data from the ongoing Phase 2 clinical trial of its product candidate GMI-1271, an E-selectin antagonist, in patients with acute myeloid leukemia (AML). The data will be presented at the June annual meetings of the American Society of Clinical Oncology (ASCO) and the European Hematology Association (EHA). The data released by ASCO and EHA, which reflect a late-January analysis, will be updated in posters presented at both meetings.
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Omeros Announces Completion of IgA Nephropathy Cohort in OMS721 Phase 2 Clinical Trial

-- Additional Positive Results Support Rapid Advancement to Phase 3 Trial --
 
SEATTLE -- Omeros Corporation (NASDAQ: OMER) today announced completion of the IgA nephropathy cohort and reported additional positive results from the first stage of the company’s Phase 2 clinical trial of OMS721 for the treatment of serious kidney disorders. All patients in the cohort have now completed the OMS721 treatment and follow-up periods. The additional Phase 2 results in IgA nephropathy patients expand on the data reported earlier this year and further demonstrate marked and statistically significant improvement in urine protein levels (proteinuria). Proteinuria reduction is associated with slowing progression of kidney functional loss, and greater proteinuria reductions are associated with progressively better prognoses. OMS721 is Omeros’ lead human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2), the effector enzyme of the complement system’s lectin pathway.
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Ceapro earns $17,768 in Q1 2017

Mr. Gilles Gagnon reports: CEAPRO INC. REPORTS 2017 FIRST QUARTER DEVELOPMENT HIGHLIGHTS AND FINANCIAL RESULTS
 
Ceapro Inc. has released its financial results for the three months ended March 31, 2017, and provided a corporate update.
Financial Highlights for the First Quarter 2017
 
Total sales of $3,183,000 for the quarter ended March 31, 2017 compared to $4,064,000 in Q1 2016;
Gross margin of $1,711,000 for the quarter ended March 31, 2017 compared to $2,834,000 in Q1 2016;
Income from operations of $193,000 for the quarter ended March 31, 2017 compared to $1,910,000 in Q1 2016;
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Minerva Provides Update on Phase 3 Design and Development Strategy for MIN-101

Advancing a new potential therapeutic paradigm for the treatment of negative symptoms, a key unmet need in schizophrenia and other brain diseases
 
Company to host conference call on May 16, 2017 at 10:30 a.m. eastern time
 
WALTHAM, Mass., May 15, 2017  -- Minerva Neurosciences, Inc. (NASDAQ:NERV), a clinical-stage biopharmaceutical company focused on the development of therapies to treat central nervous system (CNS) disorders, today announced plans for its Phase 3 and Phase 4 clinical development of MIN-101, a drug targeting negative symptoms in schizophrenia patients.  Following a recent “end-of-Phase 2” meeting with the U.S. Food and Drug Administration (FDA), the Company’s next step is the planned initiation of a pivotal Phase 3 trial with MIN-101 in the second half of 2017.
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