Celsion Announces Completion of OVATION Study and Provides Update on its Immunotherapy Trial in Advanced Stage III and IV Ovarian Cancer
86% Objective Response Rate (ORR) in Phase IB Dose Escalating Study
100% ORR and 100% R0 (Margin Negative) Surgical Resection Rate at Highest Dose Cohort
Increased Ratio of CD8+ Cells to Immunosuppressive T-cells Observed in 75% of Patients Indicating a Shift to a Pro-Immune Stimulatory Environment
LAWRENCEVILLE, N.J., July 05, 2017 -- Celsion Corporation (NASDAQ:CLSN) today provided an update on its Phase Ib dose escalating clinical trial (the OVATION Study) combining GEN-1, the Company's IL-12 gene-mediated immunotherapy, with neoadjuvant chemotherapy for the treatment of newly-diagnosed patients with Stage III and IV ovarian cancer followed by interval debulking surgery.
- Published: 05 July 2017
- Written by Editor