Lundbeck to Acquire Chelsea Therapeutics

  • By acquiring Chelsea Therapeutics, Lundbeck gains the rights to Chelsea Therapeutics' recently FDA-approved product, NORTHERATM (droxidopa), which is expected to be launched later in 2014
  • NORTHERA is an orphan neurology opportunity with strong commercial and strategic fit with Lundbeck's existing U.S. neurology franchise
  • Chelsea stockholders are entitled to USD 6.44 per share in cash and CVRs that may pay up to USD 1.50, for a total potential consideration of up to USD 7.94 per share, or USD 658 million on a fully diluted basis
Read more: Chelsea Therapeutics International ( CHTP )

Ironwood Pharmaceuticals Provides First Quarter 2014 Investor Update

– First quarter LINZESS® (linaclotide) net product sales of $60.8 million, as reported by Forest Laboratories, Inc. –
– Multi-channel Direct-to-Consumer awareness campaign
launched –

Ironwood Pharmaceuticals, Inc. (IRWD) today provided an update on its first quarter 2014 and recent business activities.

“During the first fifteen months of the LINZESS launch, we have established a strong foundation of physician experience and payer coverage for LINZESS. Now, while we continue advancing with prescribers and payers, we are intensifying our efforts to educate appropriate patients about LINZESS through a multi-channel, direct-to-consumer patient awareness campaign,” said Peter Hecht, chief executive officer of Ironwood.

Read more: Ironwood Pharmaceuticals Inc ( IRWD )

Valeant Proposes to Combine With Allergan for $48.30 in Cash and 0.83 Shares of Valeant Stock for Each Allergan Share

This Offer Represents a Substantial Premium to Allergan's Unaffected Stock Price of $116.63 on April 10, 2014, the Day Before Pershing Square Crossed the 5% Schedule 13D Ownership Level and Commenced its Rapid Accumulation Program

As Significant Shareholders in the Combined Company, Allergan Shareholders Will also Benefit from any Future Appreciation in Valeant Stock

Merger Would Create Unrivaled Platform for Growth and Value Creation with Leading Positions in High-Growth Geographies and Therapeutic Markets

Valeant Expects to Realize At Least $2.7 Billion in Annual Cost Synergies, 80% Achieved in First Six Months

Read more: Allergan Inc ( AGN )

Zogenix Announces Ruling Preventing the Implementation of Massachusetts Governor's Order that Prevented Access to Zohydro™ ER

Zogenix, Inc. (ZGNX), a pharmaceutical company developing and commercializing products for the treatment of pain-related and central nervous system (CNS) disorders, today announced that the U.S. District Court in Massachusetts entered an order, preventing the implementation of the Commonwealth's ban of Zohydro™ ER on Constitutional grounds.  This order will become effective on April 22, 2014.

The court decision today supports the importance of upholding the Constitutional principle at the heart of this case. The United States Food and Drug Administration (FDA) approved Zohydro™ ER (hydrocodone bitartrate) Extended-Release Capsules, CII, for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

Read more: Zogenix Inc ( ZGNX )

Apricus Biosciences' Partner in the United Kingdom Accepts First Shipment of Vitaros(R)

Takeda UK to be the First to Launch Vitaros(R) in Europe

Apricus Anticipates Follow-On Vitaros Product Shipments and Launches Throughout 2014

SAN DIEGO, April 16, 2014 - Apricus Biosciences, Inc. (APRI), a pharmaceutical company focusing on the development and commercialization of novel therapeutics for men's and women's health, today announced that Takeda Pharmaceuticals International GmbH, the Company's partner in the United Kingdom, has accepted the first shipment of Vitaros(R), Apricus' novel topical on-demand treatment for erectile dysfunction ("ED").

Read more: Apricus Biosciences Inc ( APRI )