Minerva Neurosciences Reports Positive Phase 1 Data With MIN-202, Selective Orexin-2 Antagonist for Treatment of Sleep Disorders Including Primary and Comorbid Insomnia

Preliminary results provide additional support for progression of MIN-202 into next stage of clinical development. Minerva developing MIN-202 in collaboration with Janssen.

WALTHAM, Mass., Jan. 21, 2015  -- Minerva Neurosciences, Inc. (NERV) today announced that preliminary results from a Phase 1 clinical study showed that treatment with MIN-202, a selective orexin-2 antagonist, resulted in significant improvements in sleep onset and sleep duration in patients with comorbid insomnia related to major depressive disorder (MDD). Preliminary results from two additional Phase 1 studies also suggest that MIN-202 is well tolerated and possesses advantageous pharmacokinetic and pharmacodynamic features. The three Phase 1 studies were conducted by Janssen Research & Development, LLC, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, as part of a collaboration to develop MIN-202 with Minerva that was facilitated by Johnson & Johnson Innovation Ltd in London.

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(Reuters) - Retail foreign exchange brokers from New Zealand to New York were nursing hefty losses from the Swiss National Bank's shock move to abandon a cap on its currency, with some even being forced out of business.

Retail broker Alpari UK filed for insolvency on Friday after customers sustained losses following the SNB's decision.

"The recent move on the Swiss franc caused by the SNB's unexpected policy reversal of capping the Swiss franc against the euro has resulted in exceptional volatility and extreme lack of liquidity," Alpari, the shirt sponsor of English Premier League club West Ham, said in a statement.

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The Conservative government will not release the federal budget until at least April, a delay meant to give Finance Minister Joe Oliver more time to assess the impact of plunging oil prices on the Canadian economy.

Mr. Oliver made the announcement Thursday in an address to the Calgary Chamber of Commerce.

“Given the current market instability, I will not bring forward our budget earlier than April. We need all the information we can obtain before finalizing our decisions,” he said, according to a copy of his prepared remarks.

The federal fiscal year begins April 1 and federal budgets are normally released in February or March.

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Bangcle and CYREN to Power Threat Detection for 500 Million Mobile Phone Users

World's Largest Mobile Application Security Provider to Deploy CYREN Security Technology

MCLEAN, Va., Dec. 10, 2014  CYREN (CYRN) and China-based Bangcle, the world's largest mobile application security provider, today announced that Bangcle will deploy CYREN's embedded technology to protect mobile applications against today's latest threats.

Bangcle helps developers guard their apps against malicious code, tampering and pirating while also protecting private customer account information. By the end of November, 400,000 mobile applications have adopted the Bangcle security app shield, which covers 500 million mobile phones globally.

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By Rachel Fox - FoxOnStocks.com

How will the S&P500 perform over the Thanksgiving Holiday?

Like many passionate traders, I’ll be poised at my computer executing trades during this choppy market week of Thanksgiving. The market will be closed on Thursday, of course, and open only half a day on Black Friday. I suspect many non-dedicated traders will be away from it all, as they prepare and travel for the Thanksgiving holiday.

My question is, “Will it be feast or famine for the S&P 500 this Thanksgiving 2014?” With many bulls and many bears giving their opinion about the health or lack of health in the market, I looked online for a guide about how the market fares during this season.

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