Alnylam and Sanofi Report Positive Topline Results from APOLLO Phase 3 Study of Patisiran in Hereditary ATTR (hATTR) Amyloidosis Patients with Polyneuropathy

– Investigational RNAi Therapeutic Patisiran Meets Primary and All Secondary Endpoints, with Highly Significant Reduction In Neuropathy Progression and Improvement in Quality of Life at 18 Months Relative to Placebo –
– Alnylam Intends to File New Drug Application (NDA) in Late 2017 and Marketing Authorisation Application (MAA) in Early 2018–
– Full Results to be Presented at 1st European ATTR Amyloidosis Meeting in November –
– Alnylam to Host Conference Call Today at 8:30 a.m. ET–
 
CAMBRIDGE, Mass. & PARIS -- Alnylam Pharmaceuticals, Inc. (Nasdaq:ALNY), the leading RNAi therapeutics company, and Sanofi Genzyme, the specialty care global business unit of Sanofi, announced today that the APOLLO Phase 3 study of patisiran, an investigational RNAi therapeutic being developed for patients with hereditary ATTR amyloidosis with polyneuropathy, met its primary efficacy endpoint and all secondary endpoints.
Read more: Alnylam Pharmaceuticals ( ALNY )

DelMar Pharmaceuticals Announces Issuance of New Patent on First-in-Class DNA-targeting Agent, VAL-083

Newly issued patent claims provide patent protection into 2033
 
VANCOUVER, British Columbia and MENLO PARK, Calif., Sept. 20, 2017 -- DelMar Pharmaceuticals, Inc. (Nasdaq: DMPI) ("DelMar" and "the Company"), a biopharmaceutical company focused on the development of new cancer therapies, today announced that the U.S. Patent and Trademark Office (USPTO) has issued to DelMar, United States Patent No. 9,759,698 covering improved analytical methods for analyzing and determining impurities in dianhydrogalactitol (VAL-083).
Read more: DelMar Pharmaceuticals ( DMPI )

Revive Therapeutics and South Carolina Research Foundation Enter into Exclusive License Agreement for Cannabinoids-Based Therapeutics in the Treatment of Liver Diseases

TORONTO, ONTARIO--(Sept. 19, 2017) - Revive Therapeutics Ltd. ("Revive" or the "Company") (TSX VENTURE:RVV)(OTCQB:RVVTF), a company focused on the research, development and commercialization of novel treatments for serious and unmet medical needs, today announced that it has entered into a license agreement with South Carolina Research Foundation ("SCRF"), under which Revive will acquire an exclusive license from SCRF to develop and commercialize a portfolio of patents based on cannabinoid-based therapeutics, such as Cannabidiol, in the treatment of liver diseases.
Read more: Revive Therapeutics Ltd ( RVV )

Prometic Reports Positive Clinical Data from Ongoing PBI-4050 Study in Alström Syndrome Patients

Sustained safety observed over 48 weeks of treatment
Beneficial clinical effects in liver sustained over 48 weeks of treatment
Positive results support requests for meetings with both FDA and EMA to define the clinical-regulatory pathway for approval of PBI-4050 for the treatment of Alström syndrome
 
LAVAL, QC, Sept. 19, 2017 - Prometic Life Sciences Inc. (TSX: PLI) (OTCQX: PFSCF) (Prometic) today announced that longer-term data from its on-going phase 2 open label clinical trial in subjects suffering from Alström Syndrome in the United Kingdom confirm that the beneficial clinical effects previously observed are sustained during prolonged treatment.
Read more: Prometic Life Sciences ( PLI )

iBio and TheoremDx Collaborate to Develop Proteins for Rapid Diagnostics Testing Products

NEW YORK, Sept. 18, 2017  -- iBio, Inc. (NYSE AMERICAN:IBIO) – iBio, with its subsidiary, iBio CDMO LLC in Bryan/College Station, Texas ("iBio CDMO"), has partnered with TheoremDx, Inc., in Edina, Minnesota, to develop proteins for rapid diagnostic testing products.
 
The collaboration will leverage the TheoremDx point-of-care diagnostic system and the protein development and manufacturing capabilities of iBio. The goal of the collaboration is to serve the citizens of the US and the world through the rapid development and manufacturing of proprietary plant proteins for point-of-care diagnostic testing products. 
Read more: iBio Inc ( IBIO )

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