HACKENSACK, N.J. and PETACH TIKVAH, Israel, Dec. 14, 2016  -- BrainStorm Cell Therapeutics Inc. (BCLI), a leading developer of adult stem cell technologies for neurodegenerative diseases, announced that new data from the Company's Phase 2 study of NurOwn® in ALS were presented by lead investigator Dr. James Berry at the 27th International Symposium on ALS/MND in Dublin, Ireland.

 

In the Phase 2 trial, levels of neurotrophic factors and inflammatory markers were measured in cerebral-spinal fluid (CSF) samples collected from patients.  In the samples of those patients treated with NurOwn, a statistically significant increase in levels of neurotrophic factors VEGF, HGF and LIF was observed from pre- to post-transplantation.  There was also a statistically significant reduction in inflammatory markers (MCP-1 and SDF-1) over this period, in patients treated with NurOwn® and this was not observed in the placebo group. 

First Tissue-Engineered Autologous Cellularized Scaffold Product Approved by the FDA

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CAMBRIDGE, Mass., Dec. 14, 2016 -- Vericel Corporation (NASDAQ:VCEL), a leading developer of expanded autologous cell therapies for the treatment of patients with serious diseases and conditions, today announced that the U.S. Food and Drug Administration (FDA) has approved MACI® (autologous cultured chondrocytes on porcine collagen membrane) for the repair of symptomatic single or multiple full-thickness cartilage defects of the knee with or without bone involvement in adults.

2016-12-12 09:04 ET - News Release -- SAN FRANCISCO --  Jaguar Animal Health, Inc. (NASDAQ:JAGX) (“Jaguar”), an animal health company focused on developing and commercializing first-in-class gastrointestinal products for companion and production animals, foals, and high value horses, today announced that it has signed a distribution agreement (the “Agreement”) with Henry Schein, Inc., the world’s largest provider of health care products and services to office-based dental, animal health and medical practitioners, for exclusive distribution of Jaguar’s Neonorm™ Foal product to all segments of the U.S. equine market.

 

Henry Schein’s animal health business, Dublin, Ohio-based Henry Schein Animal Health, employs approximately 900 team members and had 2015 net sales of $2.9 billion. With 12 strategically positioned, state-of-the-art distribution facilities and 10 inside sales centers nationwide, we believe Henry Schein Animal Health is positioned to bring a broad selection of veterinary products and strategic business solutions to more than 26,000 veterinary professionals nationwide.

2016-12-12 08:30 ET - News Release MADISON, Wis., Dec. 12, 2016 -- Cellectar Biosciences, Inc. (Nasdaq:CLRB) (the “company”), an oncology-focused clinical stage biotechnology company, today announced that the United States Patent and Trademark Office (“USPTO”) has granted patent number 9,480,754 covering the method of use for CLR 1603 to treat breast, lung, colorectal and prostate cancers as well as their associated cancer stem cells. CLR 1603 consists of Cellectar’s proprietary phospholipid drug conjugate (“PDC”) delivery platform technology using a unique chemical linker, conjugated to the chemotherapeutic agent paclitaxel.

 

This patent and the previously granted composition of matter patent provide intellectual property protection for CLR 1603 to the end of 2035. Earlier this year, the company announced that CLR 1603 showed an increased delivery of between 20 – 30 times that of paclitaxel alone to a tumor in a preclinical xenograft cancer model. Additionally, CLR 1603 did not require the use of Cremophor in its formulation, a desired feature as Cremophor has been linked to a number of serious adverse events. As a result, CLR 1603 improved formulation, combined with its targeted delivery, has the potential to significantly reduce adverse events typically associated with other paclitaxel-based therapies.