Galena Biopharma Reports Positive Outcome from the Data Safety Monitoring Board on the Two NeuVax ™ (nelipepimut-S) Clinical Trials in Combination with Trastuzumab

Both combination trials are deemed not futile and Data Safety Monitoring Board recommends that both trials continue
Interim efficacy analysis for the low-to-intermediate (HER2 1+/2+) trial now expected by the end of 2017
 
SAN RAMON, Calif., Feb. 06, 2017  -- Galena Biopharma, Inc. (NASDAQ:GALE), a biopharmaceutical company committed to the development and commercialization of hematology and oncology therapeutics that address unmet medical needs, today announced the results from a meeting of the Data Safety Monitoring Board (DSMB) for the two investigator-sponsored (IST) combination clinical trials with NeuVax™ (nelipepimut-S) plus trastuzumab.  The trials are being run in breast cancer patients to assess the ability of the combination of trastuzumab and the HER2 vaccine nelipepimut-S (administered with the immunoadjuvant granulocyte macrophage-colony stimulating factor) to prevent recurrence in the adjuvant setting.
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Amyris Provides Business Update

Will Report Record Revenue in Both Collaborations and Product Sales for 2016; Near-Term Debt Maturities Have Been Resolved; Completed Strategic Transition Out of Commodity Products
 
EMERYVILLE, Calif., Feb. 03, 2017 -- Amyris, Inc. (Nasdaq:AMRS), the industrial bioscience company, today provided an update on certain aspects of its business and financial results for 2016.
 
“We are pleased to have achieved a record year of revenue growth, and of having completed all of the 2016 strategic milestones we set out to, and we continue to make good progress on our debt structure by having resolved our near-term debt maturity issues in pushing out approximately $44 million in debt as announced just before year end,” said John Melo, Amyris President & CEO. “Also, we are meeting our expectations in securing collaborations that will result in future product sales and this is accelerating our growth rate.”
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Palatin Technologies Announces Closing of License Agreement with AMAG Pharmaceuticals for North American Rights to Rekynda ™

Will Also Report Second Quarter 2017 Results and Discuss Next Steps in its Development Programs
Teleconference and Webcast to be held on February 9, 2017
 
CRANBURY, N.J., Feb. 3, 2017  -- Palatin Technologies, Inc. (NYSE MKT: PTN) announced the closing of its license agreement with AMAG Pharmaceuticals, Inc. (Nasdaq: AMAG) for exclusive North American rights to develop and commercialize Rekynda™ (bremelanotide), an investigational product designed for on-demand treatment of hypoactive sexual desire disorder (HSDD) in pre-menopausal women.  Palatin received an initial payment of $60,000,000 under the license agreement.
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Benitec Biopharma makes significant progress in ocular program

- Data to be presented at industry leading conferences
- Development of novel viral vectors for delivery to the back of the eye
- Expanded potential of developing ddRNAi technology into ocular indications
 
SYDNEY, Feb. 2, 2017 -- Benitec Biopharma Limited (ASX:BLT; NASDAQ: BNTC; NASDAQ: BNTCW) is pleased to announce today that it has made significant progress with the Company's ddRNAi technology for the development of therapeutics for the treatment of ocular diseases.  Of particular importance is the output from Benitec's collaboration with 4D Molecular Therapeutics to identify novel viral vectors for delivery to the back of the eye using direct intravitreal injection, a commercially attractive route of administration. 
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Tenax Therapeutics Announces Top-Line Results From Phase 3 LEVO-CTS Trial in Cardiac Surgery

– Study Did Not Achieve Statistically Significant Reductions in Dual or Quad Primary Endpoints –
– Study Met Two Secondary Endpoints with Statistically Significant Reduction in Incidence of LCOS and Use of Postoperative Secondary Inotropes –
 
MORRISVILLE, N.C. -- Tenax Therapeutics, Inc. (NASDAQ: TENX), a specialty pharmaceutical company focused on identifying, developing and commercializing products for the critical care market, today announced top-line results from its Phase 3 LEVO-CTS trial. The study did not achieve statistically significant reductions in the dual endpoint of death or use of a mechanical assist device at 30 days, nor in the quad endpoint of death, myocardial infarction, need for dialysis, or use of a mechanical assist device at 30 days. However, the study demonstrated statistically significant reductions in two of three secondary endpoints including reduction in low cardiac output syndrome (LCOS) and a reduction in postoperative use of secondary inotropes. 
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